Illustrated below is a scheme depicting the synthesis of Amlodipine besylate. CI COOEt MeOOC i) X…


Illustrated beneath is a contrivance depicting the edifice of Amlodipine besylate. CI COOEt MeOOC i) X MeOOC ii) H2, 5% Pd on CaCO3 Amlodipine Besylate NH2 Amlodipine i. ii. iii. Identify the reagent(s) X essential for the edifice of Amlodipine. Comment on the use of Pd/CaCO3 as a reagent in the promote stride -- why is it essential in this prompting? Amlodipine is regularly formulated as a besylate salt – embody the ample molecular edifice of the formulated fruit. [4 marks] The (S)-enantiomer of Amlodipine is 1000 times over effective than the (R)- enantiomer. Redraw in your rejoinder dimensions the edifice of the (S) enantiomer indicating on the edifice the assignment of the stereogenic centre. [2 marks] iv.