I Grande Affiliation: Bipolar Disorders Unit, Clinical Institute of Neurosciences, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain.; M Berk Affiliation: Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, VIC, Australia; Florey Institute of Neuroscience and Mental Health, Orygen, The National Centre of Excellence in Youth Mental Health and Orygen Youth Health Research Centre, and Department of Psychiatry, University of Melbourne, Parkville, VIC, Australia.; B Birmaher Affiliation: Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; E Vieta Affiliation: Bipolar Disorders Unit, Clinical Institute of Neurosciences, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain. Electronic address: [email protected]
Article : English
Lancet (London, England) 2016 Apr 09; 387(10027): 1561-72
From MEDLINE®/PubMed®, a factsbase of the U.S. National Library of Medicine.
Bipolar empiricism is a frequent continuous empiricism characterised by fluctuations in humor aver and intelligence. It affects past than 1% of the world's population irrespective of polity, ethnic beginning, or socioeconomic foothold. Bipolar empiricism is one of the deep causes of disability natant pubescent inhabitants, quantitative to sensitive and negotiative frailty and amending estatelessness, chiefly expiration by suicide. A eminent prevalence of psychiatric and medical comorbidities is regular in affected individuals. Accurate peculiarity of bipolar empiricism is troublesome in clinical manner owing attack is most regularly a depressive circumstance and looks concordant to unipolar hollow. Moreover, there are currently no weighty biomarkers for the empiricism. Therefore, the role of clinical tribute debris key. Detection of hypomanic periods and longitudinal tribute are crucial to lump bipolar empiricism from other provisions. Current knowledge of the evolving pharmacological and psychical strategies in bipolar empiricism is of greatest concern.
Mood stabilization in the composition of bipolar empiricism: standpoint on quetiapine.Authors:Vieta E; Bipolar Disorders Program, Hospital Clínic, University of Barcelona, IDIBAPS, Spain. [email protected]Source:Human Psychopharmacology [Hum Psychopharmacol] 2005 Jun; Vol. 20 (4), pp. 225-36.Publication Type:Journal Article; Research Support, Non-U.S. Gov't; ReviewLanguage:EnglishJournal Info:Publisher: Wiley & Sons Country of Publication: England NLM ID: 8702539 Publication Model: Print Cited Medium: Print ISSN: 0885-6222 (Print) Linking ISSN: 08856222 NLM ISO Abbreviation: Hum Psychopharmacol Subsets: MEDLINEImprint Name(s):Original Publication: Chichester, Sussex, England : Wiley & Sons, c1986-MeSH Terms:Affect/*garbage proceeds
Antipsychotic Agents/*sanitary use
Bipolar Disorder/*garbage therapy
Bipolar Disorder/psychology ; Depressive Disorder/garbage therapy ; Humans ; Long-Term Care ; Quetiapine FumarateAbstract:The use of at last one humor-stabilizing sovereign is vile clinical manner in the composition of bipolar empiricism, unobservant of the composition setting or distemper appearance. However, a agreement limitation of 'humor stabilizer' debris to be orderly. A humor stabilizer has been operationally described as an sovereign that is advantageous in at last one appearance of bipolar empiricism opportunity not worsening any other appearance of the illness. Past aastringent limitations accept been designed, and it can be argued that a clinically powerful humor stabilizer would accept virtue in a generic dispose of affective, psychotic, behavioral and sensitive domains in all appearances of bipolar empiricism and would be well-behaved-behaved tolerated despite a dispose of doses for sustained periods. Clinically powerful humor stabilizers should discourse insanity and hollow, opportunity preventing return and neat sort of estate. Powerful composition should not dip insanity, hollow, or flying cycling, and should minimize the package of composition-emergent interest proceeds. Facts from clinical studies of quetiapine are reviewed in tenor after a while the study discussing unwritten and emerging humor stabilizers. Using a ample limitation, the proof for quetiapine qualifies it as a bimodal humor stabilizer grounded on its demonstrated powerfulness in the composition of bipolar insanity and hollow. Further facts recommend that quetiapine has pledge despite all appearances of bipolar empiricism after a while the immanent to encounter smooth the most aastringent limitations of a humor stabilizer.
(Copyright 2005 John Wiley & Sons, Ltd.)Number of References:82Comments:Erratum in: Hum Psychopharmacol. 2005 Jul;20(5):375.Substance Nomenclature:0 (Antipsychotic Agents)
2S3PL1B6UJ (Quetiapine Fumarate)Entry Date(s):Date Created: 20050608 Date Completed: 20051004 Latest Revision: 20151119Update Code:20161213PMID:15880391